Office of Human Research Protections (OHRP)
The Office for Human Research Protections (OHRP) provides leadership in the protection of the rights, welfare, and wellbeing of subjects involved in research conducted or supported by the U.S. Department of Health and Human Services (HHS). OHRP helps ensure this by providing clarification and guidance, developing educational programs and materials, maintaining regulatory oversight, and providing advice on ethical and regulatory issues in biomedical and social-behavioral research.
History of Human Subjects Protections
The history behind human subjects protections began in 1947 with the Nuremberg Code, developed for the Nuremberg Military Tribunal as standards by which to judge the human experimentation conducted by the Nazis. The Code captures many of what are now taken to be the basic principles governing the ethical conduct of research involving human subjects. For more about the history of human subjects protection system, please visit the following links: OHRP 45 CFR part 46 FAQs or search the Office of Human Research Protections.
Federal Policy for the Protection of Human Subjects (“Common Rule”)
OHRP Resources/Guidance Materials:
- Guidance on Engagement of Institutions in Human Subjects Research
- Guidance on Withdrawal of Subjects from Research: Data Retention and Other Related Issues
- Health Information Privacy: HIPAA Privacy Rule
- Informed Consent Checklist
- Tips on Informed Consent
- Vulnerable Populations
For Students, Faculty and Staff:
Office for Human Research Protections (OHRP) Educational Videos are now available on YouTube!
OHRP is pleased to announce the availability for the first time of educational videos on the HHS YouTube channel. The videos include "Research Use of Human Biological Specimens and Other Private Information" and "Reviewing and Reporting Unanticipated Problems and Adverse Events," (both of which premiered and are still available also in RealPlayer format), in addition to two new videos "Institutional Review Board (IRB) Membership" and "General Informed Consent Requirements Parts I (Research Investigator) and II (Research Subject)."