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College of Science and Engineering > Faculty and Staff Directory

Faculty and Staff Directory

Joseph Langenhan

Associate Professor
Chemistry

Curriculum Vitae

Contact Information

Phone

206.296.2368

Email

langenha@seattleu.edu

Office

BANN 615

Teaching and Research Interests

Dr. Langenhan’s teaching interests include Organic Chemistry and Bioorganic Chemistry.

Dr. Langenhan’s research involves redesigning biological molecules, with the twin goals of understanding their functions and modulating their activities. Current research efforts are focused on modified oligonucleotides and antimicrobial agents.

Biography

After receiving a B.S. in Chemistry from Allegheny College in 1998, Dr. Langenhan pursued graduate studies with Professor Samuel H. Gellman at the University of Wisconsin-Madison and earned a Ph.D. in Organic Chemistry in 2003. He then conducted two years of post-doctoral research with Professor Jon S. Thorson at the Laboratory for Biosynthetic Chemistry in the School of Pharmacy at the University of Wisconsin-Madison before moving to Seattle University.

 

Recent Publications


         (undergraduate co-authors underlined)  

 

8.   Langenhan, J.M.; Mullarky, E.; Rohlfing, J.; Rogalsky, D.R.; Werner, H.; Tjaden, A. ; Rozal, L.  "Total Synthesis of Amphimedosides A-C," manuscript in preparation.  

7.   Langenhan, J.M.; Endo, M.M.; Engle, J.M.; Fukumoto, L.L.; Rogalsky, D.R.; Slevin, L.K.; Fay, L.R.; Lucker, R.W.; Rohlfing, J.R.; Smith, K.R.; Tjaden, A.E.; Werner, H.M.Carbohydr. Res., in press.  “Synthesis and Biological Evaluation of RON-Neoglycosides as Tumor Cytotoxins.”  

6.   Alaimo, P.J.; Langenhan, J.M.; Suydam, I.T. “Thinking like a scientist in the organic chemistry lab: Designing experiments to generate data for analysis and discussion,” manuscript in preparation.  

5.   Iyer, A.; Zhou, M.; Azad, N.; Elbaz, H.; Wang, L.; Rogalsky, D.K.; Rojanasakul, Y.; O’Doherty, G.A.; Langenhan, J.M. ACS Med. Chem. Lett.2010, 1, 326-330.  “A Direct Comparison of the Anticancer Activities of Digitoxin MeON-Neoglycosides and O-Glycosides.”  

4.   Alaimo, P.J.; Marshall, A.-L.; Andrews, D.M.; Langenhan, J.M. Org. Synth.2010, 87, 192-200.  “1,3,5-Triacetylbenzene.”  

3.   Langenhan, J.M.; Alaimo, P.J.; Tanner, M.J.; Ferrenberg, S.M., J. Chem. Educ., 2010, 87, 856-861. “Safety teams: An Approach to Engage Students in Laboratory Safety.”  

·         Chemical & Engineering News blog feature: http://cenblog.org/the-safety-zone/2010/07/undergrad-laboratory-safety-teams/ (7/7/2010)  

·         Editorial highlight in J. Chem. Educ.2010, 87, 764-765  

2.   Alaimo, P.J.; Bean, J.C.; Langenhan, J.M.; Nichols, L.  Writing Across the Curriculum Journal, 2009, 20, 17-32. “Eliminating Lab Reports: A Rhetorical Approach for Teaching the Scientific Paper in Sophomore Organic Chemistry.”  

·         Podcast highlight in Science: http://www.sciencemag.org/content/332/6032/919/suppl/D  

1.   Langenhan, J.M.; Engle, J.M.; Slevin, L.K.; Fay, L.R.; Lucker, R.W.; Smith, K.R.; Endo, M.M.Bioorg. Med. Chem. Lett.2008, 18, 670-673.  “Modifying the Glycosidic Linkage in Digitoxin Analogs Provides Selective Cytotoxins.”  

   

 

 

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Seattle University

College of
Science and Engineering

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